All About Vimpat — An Epilepsy Add-on Treatment

Approved to treat partial-onset seizures in adults 17 years or older with epilepsy.

VIMPAT is a prescription medicine that has been approved to treat partial-onset seizures in people 17 years of age and older. It is approved to be used alone or with other seizure medicines.

When VIMPAT is taken alone, it may be the only seizure medicine you need to treat your partial-onset seizures.

When VIMPAT is added to existing seizure medicines, it may reduce your partial-onset seizures by 50% or more. VIMPAT has been proven to significantly reduce the number of partial-onset seizures when added to the most common anti-seizure medicines including Depakote®, Dilantin®, Keppra®*, Lamictal®, phenobarbital, Tegretol®, Topamax®, Trileptal®, and Zonegran®.

Most common side effects for VIMPAT

The most common side effects of VIMPAT include dizziness, headache, nausea, and double vision. Work with your doctor to decide if VIMPAT may be right for you. Report side effects you may experience with VIMPAT to FDA at 1-800-FDA-1088. You may also report side effects to UCB, Inc. at UCBCares (1-844-599-CARE [2273]).

“I talked to my doctor. He agreed we needed to do more." — Veronica C., an epilepsy patient currently taking VIMPAT for partial-onset seizures

What is VIMPAT?

VIMPAT is a prescription medicine that can be used alone or with other medicines to treat partial-onset seizures in people 17 years of age and older.

What is the most important information I should know about VIMPAT?

Do not stop taking VIMPAT without first talking to your healthcare provider.

Stopping VIMPAT suddenly can cause serious problems. Stopping seizure medicine suddenly in a patient who has epilepsy can cause seizures that will not stop.

VIMPAT can cause serious side effects, including:

1.Like other antiepileptic drugs, VIMPAT may cause suicidal thoughts or actions in a very small number of people, about 1 in 500.

IMPORTANT SAFETY INFORMATION (Continued)

Call a healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you:

  • thoughts about suicide or dying
  • attempt to commit suicide
  • new or worse depression
  • new or worse anxiety
  • feeling agitated or restless
  • panic attacks
  • trouble sleeping (insomnia)
  • new or worse irritability
  • acting aggressive, being angry, or violent
  • acting on dangerous impulses
  • an extreme increase in activity and talking (mania)
  • other unusual changes in behavior or mood

2.VIMPAT may cause you to feel dizzy, have double vision, feel sleepy, or have problems with coordination and walking. Do not drive, operate heavy machinery, or do other dangerous activities until you know how VIMPAT affects you.

3.VIMPAT may cause you to have an irregular heartbeat or may cause you to faint. Call your healthcare provider if you have:

  • fast, slow, or pounding heartbeat
  • shortness of breath
  • feel lightheaded
  • fainted or if you feel like you are going to faint

4.VIMPAT is a federally controlled substance (C-V) because it can be abused or lead to drug dependence. Keep your VIMPAT in a safe place, to protect it from theft. Never give your VIMPAT to anyone else, because it may harm them.

What should I tell my healthcare provider before taking VIMPAT?

Before you take VIMPAT, tell your healthcare provider, if you:

  • have or have had depression, mood problems or suicidal thoughts or behavior
  • have heart problems
  • have kidney problems
  • have liver problems
  • have abused prescription medicines, street drugs or alcohol in the past
  • have any other medical problems
  • are pregnant or plan to become pregnant
  • are breastfeeding or plan to breastfeed.

What are the possible side effects of VIMPAT?

See “What is the most important information I should know about VIMPAT?”.

VIMPAT may cause other serious side effects including:

VIMPAT may cause a serious allergic reaction that may affect your skin or other parts of your body such as your liver or blood cells. Call your healthcare provider right away if you have:

  • a skin rash, hives
  • fever or swollen glands that do not go away
  • shortness of breath, swelling of the legs, yellowing of the skin or whites of the eyes, or dark urine.

The most common side effects of VIMPAT include:

  • dizzines
  • headache
  • double vision
  • nausea

These are not all of the possible side effects of VIMPAT. For more information ask your healthcare provider or pharmacist. Tell your healthcare provider about any side effect that bothers you or that does not go away. Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to UCB, Inc. at UCBCares (1-844-599-CARE [2273]).

Please see additional patient information in the Medication Guide. This information does not take the place of talking with your healthcare provider about your condition or your treatment. For more information, go to www.vimpat.com or call 1-844-599-2273.

VIMPAT® oral solution contains aspartame, a source of phenylalanine.

Common Adverse Reactions

In clinical trials, the most common side effects seen with VIMPAT were dizziness, headache, nausea, and double vision.

Talk to your healthcare provider about other possible side effects with VIMPAT. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see additional patient information in the Patient Medication Guide. This information does not take the place of talking with your healthcare provider about your condition or your treatment.


*KEPPRA (LEVETIRACETAM)

INDICATION

KEPPRA XR (levetiracetam) is a prescription medicine taken by mouth that is used with other medicines to treat partial onset seizures in people 12 years of age and older with epilepsy. KEPPRA XR is available in two dosage strengths: 500mg and 750mg tablets.

KEPPRA (levetiracetam) is a prescription medicine taken by mouth that is used with other medicines to treat primary generalized tonic-clonic seizures in people 6 years of age and older with certain types of generalized epilepsy, myoclonic seizures in people 12 years of age and older with juvenile myoclonic epilepsy, and partial onset seizures in people 1 month of age and older with epilepsy. KEPPRA is available in tablet strengths of 250mg, 500mg, 750mg, and 1000mg, and 100mg of levetiracetam per mL oral solution.

IMPORTANT SAFETY INFORMATION

KEPPRA and KEPPRA XR may not be for everyone. Ask your healthcare provider if KEPPRA or KEPPRA XR is right for you.

Warnings and Precautions

Antiepileptic drugs, including KEPPRA and KEPPRA XR, may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Call your healthcare provider right away if you have new or worsening symptoms of depression, any unusual changes in mood or behavior, or suicidal thoughts, behavior, or thoughts about self harm that you have never had before or may be worse than before. KEPPRA and KEPPRA XR may cause extreme sleepiness, tiredness, and weakness, and problems with muscle coordination. You should not drive, operate machinery or do other dangerous activities until you know how KEPPRA or KEPPRA XR affects you. Call your healthcare provider right away if you have a skin rash. Serious skin rashes can happen after you start taking KEPPRA and KEPPRA XR. There is no way to tell if a mild rash will become a serious reaction. Do not stop taking KEPPRA or KEPPRA XR unless instructed by your healthcare provider. Stopping a seizure medication all at once can cause seizures that will not stop, a very serious problem.

Common Adverse Reactions

In clinical trials, the most common side effects seen with KEPPRA XR and other formulations of KEPPRA include sleepiness, weakness, dizziness, and infection.

In clinical trials, the most common side effects seen in people who take KEPPRA include sleepiness, weakness, dizziness, and infection. In addition to those previously listed, the most common side effects seen in children who take KEPPRA include tiredness, acting aggressive, nasal congestion, decreased appetite, and irritability.

Talk to your healthcare provider about other possible side effects with KEPPRA or KEPPRA XR. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. Please see additional patient information in the KEPPRA and KEPPRA XR Patient Medication Guide at the end of the full prescribing information. This information does not take the place of talking with your healthcare provider about your condition or your treatment.


Contact Information

If you have any questions or want more information, please contact UCBCares at 1-844-599-CARE (2273) or UCBCares@UCB.com. We're here to help.

Veronica - views on treatment and not selling

Important Safety Information Read the Transcript

Display transcript content....